The isotopic ratio B-11/B-10 of gas in diffuse interstellar clouds tow
ard zeta Oph, kappa Ori, and delta Sco is measured using HST/Goddard H
igh Resolution Spectrograph echelle spectra of the B Pi 1362 Angstrom
line. To within the errors of measurement, the three lines of sight gi
ve identical results for a mean value of B-11/B-10 = 3.4 +/- 0.7, a va
lue quite similar to the solar system ratio of 4.05. These results sho
w that the latter value is not highly anomalous and that a ratio highe
r than 2.5, as predicted for boron produced from spallation reactions
controlled by high-energy cosmic rays, most probably requires a genera
l explanation. The observed ratio is consistent with additional boron
production either by spallation by low-energy (''Orion'') cosmic rays
or by neutrino-induced spallation of carbon in Type II supernovae. The
total abundance of B in the diffuse clouds is a factor of 5 less than
the meteoritic value. This depletion of B is consistent with that fou
nd for Cu and Ga, two elements with a condensation temperature similar
to B.