ELECTROCHEMICAL STUDY OF ACID-BASE PROPERTIES OF SOME 2,5-DIHYDRO-1,3,4-THIADIAZOLES IN AQUEOUS-ETHANOLIC SOLUTIONS

Authors
TUROWSKA M MLOSTON G KRZYCZMONIK P RACZAK J ROMANSKI J
Citation
M. Turowska et al., ELECTROCHEMICAL STUDY OF ACID-BASE PROPERTIES OF SOME 2,5-DIHYDRO-1,3,4-THIADIAZOLES IN AQUEOUS-ETHANOLIC SOLUTIONS, Collection of Czechoslovak Chemical Communications, 63(1), 1998, pp. 31-41
Citations number
34
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
63
Issue
1
Year of publication
1998
Pages
31 - 41
Database
ISI
SICI code
0010-0765(1998)63:1<31:ESOAPO>2.0.ZU;2-R
Abstract
The dissociation constants K-a for spherically crowded 2'- and 2,5-sub stituted thiadiazolines and their protonated forms in 45% (v/v) aqueou s-ethanolic solutions (ionic strength m = 0.1) were determined using t he pH-metric method. All the thiadiazoles are weak bases. Some of them showed also weak acidic properties. The formation enthalpies have bee n calculated using the MNDO method. On the basis of the obtained resul ts the mechanism of the protonation process is discussed.