R. Anderson et al., EARLY STAGES IN MALE GERM-CELL DIFFERENTIATION IN THE MOUSE - REVIEW ARTICLE, APMIS. Acta pathologica, microbiologica et immunologica Scandinavica, 106(1), 1998, pp. 127-132
Primordial germ cells arise during gastrulation and migrate from the h
indgut into the gonad primordium during early organogenesis. In this a
rticle, we discuss factors that control migration, proliferation and t
argeting of the PGCs. In particular we discuss how changes in adhesive
ness control germ cell positioning in the gonad, and the molecules inv
olved.