TOTAL SYNTHESIS OF ANTIBIOTIC, MICROCOCCIN-P, FROM 2,3,6-POLYTHIAZOLESUBSTITUTED PYRIDINE SKELETON [FRAGMENT A-C]

Authors
SHIN C OKUMURA K SHIGEKUNI M NAKAMURA Y
Citation
C. Shin et al., TOTAL SYNTHESIS OF ANTIBIOTIC, MICROCOCCIN-P, FROM 2,3,6-POLYTHIAZOLESUBSTITUTED PYRIDINE SKELETON [FRAGMENT A-C], Chemistry Letters, (2), 1998, pp. 139-140
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
2
Year of publication
1998
Pages
139 - 140
Database
ISI
SICI code
0366-7022(1998):2<139:TSOAMF>2.0.ZU;2-K
Abstract
Total synthesis of an antibiotic, micrococcin P, was first accomplishe d by the coupling of a 2,3,6-polythiazole-substituted pyridine skeleto n [Fragment A-C] with the independently synthesized Fragments B and D, and then deprotection with trifluoroacetic acid and final intramolecu lar cyclization using BOP as condensing agent.