ABNORMAL FSH HYPERSECRETION AS AN ENDOCRINOLOGIC MANIFESTATION OF POEMS SYNDROME

Two patients with POEMS syndrome had high basal levels of FSH in the a bsence of primary hypogonadism. They were fertile eugonadal men with n ormal serum testosterone and estradiol levels. Provocation with LH-rel easing hormone revealed blunted response of FSH secretion, but normal response of LH secretion in both patients, and one had pituitary micro adenoma on brain MRI. This report adds primary FSH hypersecretion in t he absence of primary testicular failure to the list of endocrinopathy of POEMS syndrome.