SUCCESSFUL TREATMENT OF BLEEDING FROM COLONIC ANGIODYSPLASIAS WITH TRANEXAMIC ACID IN A HEMODIALYSIS PATIENT

Colonic angiodysplasias are a common source of gastrointestinal bleedi ng in patients with end-stage renal disease (ESRD), It is well known t hat bleeding from angiodysplasias can be a difficult therapeutic probl em, This report describes a hemodialysis patient who suffered acute (m assive) and chronic gastrointestinal bleeding from colonic angiodyspla sias. Because endoscopic ablation could not be performed and resection of the colon was refused, pharmacological treatment with the antifibr inolytic agent tranexamic acid was attempted, A successful management of both the acute and chronic bleeding was achieved, No complications in terms of arterial or venous thrombosis were observed, (C) 1998 by t he National Kidney Foundation, Inc.