UNUSUAL NASAL AND ORBITAL INVOLVEMENT OF GLIOBLASTOMA-MULTIFORME - A CASE-REPORT AND REVIEW OF THE LITERATURE

We describe a case of glioblastoma treated with chemoradiotherapy that spread to the dura mater with direct invasion of the skull base, prot rusion into the homolateral nasal fossa, and penetrated of the frontal sinus, the orbital wall and the ethmoidal sinuses. Only eight cases o f glioblastoma showing this development have been described in the lit erature; one of these, however, had a sarcomatous component which was absent in our case.