T. Gaspar et al., ATYPICAL METABOLISMS AND BIOCHEMICAL CYCLES IMPOSING THE CANCEROUS STATE ON PLANT-CELLS, Plant growth regulation, 24(2), 1998, pp. 135-144
The biological, morphological and biochemical characteristics which de
fine plant cancer cells at the end of a neoplasic progression in the a
bsence of pathogens and which distinguish them from tumorous cells are
summarized. Such plant cancer cells have in common with animal cancer
cells many metabolic disturbances. The present paper reviews the bioc
hemical changes in nitrogen, carbon, sugar and heme metabolisms which
contribute to polyamine (PAs) accumulation. It indicates how these cha
nges are interconnected and even form between each other biochemical c
ycles which likely maintain these cells in their irreversible state. T
he role of these cycles in the maintenance of such cells under a proba
ble permanent oxidative stress is debated.