EFFECT OF REPEATED ORAL INFECTION OF HAMSTERS WITH SCRAPIE

Authors
DIRINGER H ROEHMEL J BEEKES M
Citation
H. Diringer et al., EFFECT OF REPEATED ORAL INFECTION OF HAMSTERS WITH SCRAPIE, Journal of General Virology, 79, 1998, pp. 609-612
Citations number
12
Categorie Soggetti
Virology,"Biothechnology & Applied Migrobiology
Journal title
Journal of General Virology → ACNP
ISSN journal
00221317
Volume
79
Year of publication
1998
Part
3
Pages
609 - 612
Database
ISI
SICI code
0022-1317(1998)79:<609:EOROIO>2.0.ZU;2-O
Abstract
The development of a transmissible spongiform encephalopathy upon upta ke of the infectious agent in feed was studied in the model system scr apie in hamsters. Compared to single dosing, repeated dosing caused di sease at a considerable higher incidence. The risk of infection was hi gher when the time interval between repetitive dosing was short. There was a statistically significant trend of clearance of infectivity wit h time.