Transcranial Doppler ultrasound is capable of detecting microembolic m
aterial, both gaseous and solid, within the intracranial cerebral arte
ries. To avoid discrediting this promising and exciting new technique,
experts in this field met in January 1997 in Frankfurt, Germany, to d
iscuss the limitations and problems of embolus detection and to determ
ine guidelines for its proper use in clinical practice, as well as in
scientific investigations. In particular, the authors suggest that stu
dies report the following parameters: (1) ultrasound device, (2) trans
ducer type and size, (3) insonated artery, (4) insonation depth, (5) a
lgorithms for signal intensity measurement, (6) scale settings, (7) de
tection threshold, (8) axial extension of sample volume, (9) fast Four
ier transform (FFT) size (number of points used), (10) FFT length (tim
e), (1 1) FFT overlap, (12) transmitted ultrasound frequency, (13) hig
h-pass filter settings, and (14) recording time. There was agreement t
hat no current system of automatic embolus detection has the required
sensitivity and specificity for clinical use.