Background. Patients with chronic medical diseases may have depression
that is not recognized by their primary care physicians. Objectives.
We aimed to examine the application of Zung's Self-Rating Depression S
cale (SDS) in the screening of depression in primary care patients wit
h chronic medical diseases in a Chinese population. Methods. We studie
d 268 patients with chronic medical diseases in the Family Medicine Ou
tpatient Clinic using a structured questionnaire including basic demog
raphic data, a Chinese version of the SDS and a rating for the self-pe
rceived severity of physical condition. The severity of chronic medica
l diseases was assessed by the authors using the Duke University Sever
ity of Illness Scale from a chart audit. Fifty patients were randomly
selected for a diagnostic interview according to the DSM-IV criteria.
The construct validity and internal consistency reliability, sensitivi
ty and specificity of the SDS were examined. Results. The results reve
aled that the SDS has good construct validity and internal consistent
reliability in the evaluation of depression in Chinese patients with c
hronic medical diseases. A cut-off point of 55 had a sensitivity of 66
.7% and a specificity of 90.0%. Depressed patients reported more cogni
tive symptoms than depressed affect and physical symptoms. Female pati
ents had more severe depressed affect than male patients, but males ha
d more prominent diurnal variation of mood than females. Conclusions.
We concluded that SDS can be a good screening tool for depression in C
hinese patients with chronic medical diseases. Owing to constraints in
the expression of sexual desire in the Chinese, elderly subjects tend
ed to report loss of libido in the response to the SDS.