THE COMPRESSIBILITIES OF LIQUID-PHASE HOST-GUEST SYSTEMS

The compressibilities of seven liquid phase, macrocyclic host-guest sy stems were determined at approximately 25 degrees C and 3.4 x 10(7) Pa . Each two-component system consisted of a cyclodextrin, a calixarene, or a crown ether as host and an appropriate solvent as guest. In each case studied, the host-guest system was found to be less compressible than the pure solvent, with the differences ranging from similar to 2 to similar to 18% Of the magnitudes of the pure solvent compressibili ties. These findings have enabled us to better understand how strong, ambient pressure, intermolecular host-guest interactions influence the compressibility of solutions. Both inclusion and solvation contribute .