HYDRODYNAMIC CHROMATOGRAPHY OF SOLUBLE MACROMOLECULES OF COLUMNS PACKED WITH SUBMICRON NONPOROUS SILICA SPHERES

Authors
OOSTERVINK R KRAAK JC POPPE H
Citation
R. Oostervink et al., HYDRODYNAMIC CHROMATOGRAPHY OF SOLUBLE MACROMOLECULES OF COLUMNS PACKED WITH SUBMICRON NONPOROUS SILICA SPHERES, American laboratory, 30(6), 1998, pp. 24
Citations number
10
Categorie Soggetti
Instument & Instrumentation","Chemistry Analytical
Journal title
American laboratory → ACNP
ISSN journal
00447749
Volume
30
Issue
6
Year of publication
1998
Database
ISI
SICI code
0044-7749(1998)30:6<24:HCOSMO>2.0.ZU;2-P
Abstract
This paper describes an application of hydrodynamic chromatography (HD C) for the separation of macromolecules. Because the HDC separation of molecules with molecular masses in the range of 10(4)-10(7) D require s a column diameter of about 1 mu m, detection can present problems. T o overcome this problem, an approach using a packed column is presente d.