AN IMPROVED AND PRACTICAL PROCEDURE FOR THE SYNTHESIS OF SUBSTITUTED PHENYLACETYLPYRIDINES

Authors
JOURNET M CAI DW LARSEN RD REIDER PJ
Citation
M. Journet et al., AN IMPROVED AND PRACTICAL PROCEDURE FOR THE SYNTHESIS OF SUBSTITUTED PHENYLACETYLPYRIDINES, Tetrahedron letters, 39(13), 1998, pp. 1717-1720
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
13
Year of publication
1998
Pages
1717 - 1720
Database
ISI
SICI code
0040-4039(1998)39:13<1717:AIAPPF>2.0.ZU;2-Y
Abstract
A general procedure for the synthesis of substituted phenylacetylpyrid ines in excellent yields is described using a Horner-Emmons condensati on between alpha-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature. (C) 1998 Els evier Science Ltd. All rights reserved.