BENZIMIDAZOLE RECEPTORS FOR CARBOXYLIC-ACIDS

Citation
M. Almaraz et al., BENZIMIDAZOLE RECEPTORS FOR CARBOXYLIC-ACIDS, Tetrahedron letters, 39(13), 1998, pp. 1811-1814
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
39
Issue
13
Year of publication
1998
Pages
1811 - 1814
Database
ISI
SICI code
0040-4039(1998)39:13<1811:BRFC>2.0.ZU;2-4
Abstract
Combination of an aminobenzimidazole with a chromenone unit provides a receptor for carboxylic acids or primary amides. This host is highly selective for carboxylic acids with K-ass above 10(6) M-1 while amides only bind weakly with association constants in the order of hundreds of M-1. (C) 1998 Elsevier Science Ltd. All rights reserved.