TRICHOFLECTIN, A BIOACTIVE AZAPHILONE FROM THE ASCOMYCETE TRICHOPEZIZELLA-NIDULUS

Authors
THINES E ANKE H STERNER O
Citation
E. Thines et al., TRICHOFLECTIN, A BIOACTIVE AZAPHILONE FROM THE ASCOMYCETE TRICHOPEZIZELLA-NIDULUS, Journal of natural products, 61(2), 1998, pp. 306-308
Citations number
9
Categorie Soggetti
Chemistry Medicinal","Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
61
Issue
2
Year of publication
1998
Pages
306 - 308
Database
ISI
SICI code
0163-3864(1998)61:2<306:TABAFT>2.0.ZU;2-B
Abstract
Trichoflectin (1), a new azaphilone belonging to the deflectin series, 6-deoxy-7-O-demethyl-3,4-anhydrofusarubin (2), and 6-deoxy-3,4-anhydr ofusarubin (3) were isolated from submerged cultures of the ascomycete Trichopezizella nidulus. All compounds showed antimicrobial activity and inhibited dihydroxynaphthalene melanin biosynthesis in fungi. The structure of trichoflectin (1) was elucidated by spectroscopic methods .