HELICASES - A UNIFYING STRUCTURAL THEME

Authors
BIRD LE SUBRAMANYA HS WIGLEY DB
Citation
Le. Bird et al., HELICASES - A UNIFYING STRUCTURAL THEME, Current opinion in structural biology, 8(1), 1998, pp. 14-18
Citations number
47
Categorie Soggetti
Cell Biology",Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
8
Issue
1
Year of publication
1998
Pages
14 - 18
Database
ISI
SICI code
0959-440X(1998)8:1<14:H-AUST>2.0.ZU;2-#
Abstract
The recent structure determinations of PcrA DNA helicase, NS3 RNA heli case, and Rep DNA helicase have revealed similarities between their fo lds. When these data are examined with sequence and biochemical analys es, as well as microscopy studies of hexameric helicases, a picture of a unifying structure and mechanism for all helicases is beginning to emerge.