In industrialized countries, tobacco smoking is the main cause of prev
entable morbidity and premature deaths. Although mortality attributabl
e to smoking has already been estimated for the population of the prov
ince of Quebec, it has never been studied on a regional basis. We calc
ulated the mortality attributable to smoking by socio-sanitary regions
of the province of Quebec for 10 fatal diseases positively associated
with smoking. The calculations were made for the years 1984 through 1
993 caking into account Canadian Census data (demographic variables),
the Sante-Quebec survey (prevalence of smoking), the death registry of
the ''Bureau de la statistique du Quebec'' (mortality data), and the
American cohort of the ''Cancer Prevention Study II'' (relative risks)
. For the diseases investigated, 24,637 and 62,711 deaths were attribu
table to smoking for women and men respectively-during the period stud
ied, thus representing 29.4% and 51.2% of attributable percentages. Th
ere is no statistical difference between the regions, which indicates
a general problem for all the province. These data again confirm the i
ncredible impact of smoking on public health. The struggle against smo
king should be a primary area For action for the benefit of all Quebec
ers.