Study Design. A longitudinal observational study of primary care patie
nts with low back pain. Objectives. 1) To describe medications prescri
bed for back pain, 2) to identify patient characteristics associated w
ith type of drug therapy, 3) to determine if the prescription of certa
in drugs is associated with better outcomes, and 4) to compare physici
an prescribing behavior with national guidelines. Summary of Backgroun
d Data, Few previous studies have focused on medication prescribing pa
tterns for back pain in primary care. Methods. Two-hundred nineteen pa
tients aged 20-69 years who were making a first visit for an episode o
f back pain were studied. After the visit, patients completed question
naires regarding sociodemographic characteristics, health status, back
pain experience, and use of medications. Symptom severity and dysfunc
tion were assessed by telephone 1 week after the visit. Results. Sixty
-nine percent of patients were prescribed nonsteroidal anti-inflammato
ry drugs, 35% muscle relaxants, 12% narcotics, and 4% acetaminophen. T
wenty percent received no medications. Patients were more likely to re
ceive medications if they had a desire for medication, pain below the
knee, less than 3 weeks of pain before visit, more severe symptoms, or
greater dysfunction. Patients with more severe symptoms were more lik
ely to receive narcotics or muscle relaxants. Patients with greater dy
sfunction were also more likely to receive narcotics. Type of drug the
rapy predicted symptom severity but not dysfunction after 1 week. Cont
rolling for other factors, those receiving medications had less severe
symptoms after 1 week than patients who received no medication. Patie
nts receiving both muscle relaxants and nonsteroidal anti-inflammatory
drugs had the best outcomes. Medication use for back pain in this hea
lth maintenance organization was generally concordant with national gu
idelines. Conclusions, Nonsteroidal anti-inflammatory drugs, often aug
mented by muscle relaxants, are a standard medical treatment for back
pain in primary care. In this observational study, patients prescribed
medications, particularly muscle relaxants, reported less severe symp
toms after 1 week than those receiving no medications. However, random
ized trials are needed to determine which medications or combinations
of medications are most effective.