In the mouse, offspring born from mature fathers exhibit better behavi
oural performances (for spontaneous activity in both sex and learning
capacity in males) than those born from post-pubescent fathers. These
behavioural variations are not accompanied by other obvious modificati
ons. They could correspond to what has been observed in man relating t
o the results in a psychometric test undergone by male progeny born fr
om very young to mature fathers, These data and those which show a dec
rease in mental performance in rats and human males born from mature t
o senescent fathers suggest the participation of some genetic factors
in these phenomena.