The neuropathology of trauma is reviewed based on the mechanism of inj
ury. Pathology is divided into primary and secondary injury, based on
the relationship to the time of injury. It is further divided by mecha
nism, with primary impact injury including skull fracture, epidural he
matoma, brain contusion and laceration, and intracerebral hemorrhage;
primary inertial injury including subdural hematoma, diffuse axonal in
jury, and diffuse vascular injury; and secondary injury including hypo
xia/ischemia, brain swelling, infection, and increased intracranial pr
essure. The neuropathology of child abuse is also reviewed.