Kd. Montgomery et al., CLINICAL AND PATHOLOGICAL FINDINGS IN HEMOCHROMATOSIS HIP ARTHROPATHY, Clinical orthopaedics and related research, (347), 1998, pp. 179-187
During a 9-year period, 15 patients with hemochromatosis hip arthropat
hy required 19 total hip arthroplasties for disabling hip pain, Preope
rative presentation, hip function, pathologic evaluation of the femora
l head, and radiographic findings were reviewed, Postoperative followu
p averaging 5.7 years (range, 2-11 years) was performed to assess hip
pain and function after total hip arthroplasty, The average preoperati
ve Hospital for Special Surgery hip score was 15 points (range, 4-24 p
oints), and this improved to 30 points (range, 4-38 points) after tota
l hip arthroplasty, Only one of 15 patients required revision surgery
at 10 years for acetabular loosening, All other patients were pain fre
e, with improved function at latest followup, Histologic evaluation of
the resected femoral heads revealed evidence of primary or secondary
osteonecrosis in seven of 19 (37%) specimens, Articular cartilage avul
sion at the level of the tidemark was identified in eight of 19 (42%)
specimens, and calcium pyrophosphate deposition was identified in five
of 19 (26%) specimens, These pathologic findings suggest a predictabl
e progression of the arthritic process in patients with hemochromatosi
s.