Background: Ectopic pituitary adenomas are rare. Only 29 cases are rep
orted in the literature. The clivus was involved in some cases but sel
la turcica was occasionally involved. Clinical Presentation: Headache
was the first symptom of a 47-year-old woman. Radiological examination
diagnosed a clivus tumour. No connection with the pituitary gland was
observed. Pre-operative diagnosis was metastasis of an unknown cancer
. Intervention: By a transphenoidal approach, we removed a haemorrhagi
c tumour. No connection between the normal pituitary gland and the tum
our was observed. Neuropathological analysis showed a prolactinoma. Co
nclusion: We report a rare case of an ectopic prolactinoma in the cliv
us unrelated to the pituitary gland. Only one other case has been repo
rted in the literature.