ASYMMETRIC HYDROSILATION OF ACETOPHENONE CATALYZED BY A CHIRAL THIAZOLIDINE-RHODIUM(I) COMPLEX

Authors
LI H YAO JS HE BL
Citation
H. Li et al., ASYMMETRIC HYDROSILATION OF ACETOPHENONE CATALYZED BY A CHIRAL THIAZOLIDINE-RHODIUM(I) COMPLEX, Huaxue xuebao, 56(2), 1998, pp. 189-193
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Huaxue xuebao → ACNP
ISSN journal
05677351
Volume
56
Issue
2
Year of publication
1998
Pages
189 - 193
Database
ISI
SICI code
0567-7351(1998)56:2<189:AHOACB>2.0.ZU;2-1
Abstract
A chiral ligand of 2-(alpha-pyridyl)-4-carbomethoxy-1, 3-thiazolidine was synthesized by condensation of L-methyl cysteinate with alpha-pyri dylaldehyde. The Rh( I) complex generated in situ by reaction of the c hiral ligand with [Rh(COD)](2) was used to catalyze the asymmetric hyd rosilation of acetophenone. The chemical and optical yields of the rea ction are up to 91% and 82.1% e. e. respectively. The influences of re action conditions on the behaviour of the catalyst were examined.