J. Hoher et al., LOCAL AND INTRAARTICULAR INFILTRATION OF BUPIVACAINE BEFORE SURGERY -EFFECT ON POSTOPERATIVE PAIN AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION, Arthroscopy, 13(2), 1997, pp. 210-217
In a double-blind, randomized trial, 40 patients undergoing open anter
ior cruciate ligament (ACL) reconstruction using a bone-patellar tendo
n-bone autograft were randomly allocated to two groups: group A (n = 2
0) received an intra-articular instillation of 20 mt bupivacaine (0.25
%) and a local infiltration of 20 mt bupivacaine (0.5%) 15 minutes bef
ore surgery. Group B (n = 20) received an injection of saline solution
in the same manner. Patient-controlled on-demand analgesia (PCA) with
intravenous piritramid was used for postoperative pain control. A sig
nificant decrease in pain scores on a visual analog scale (VAS scale,
0 to 10) was found in the bupivacaine group (group A) at bedrest on th
e day of surgery only (pain score, 5.5 v 7.3 (scale, 0 to 10), P < .05
). At all other times, no significant differences were found. The over
all supplemental opioid requirements were not different between the st
udy groups (63.9 v 62.6 mg piritramid/72 hours). A long-lasting, clini
cally relevant, pain-reducing effect with infiltration of bupivacaine
before surgery could not be shown with this study.