USE OF TRANS-SIALIDASE INHIBITION ASSAY IN A POPULATION SEROLOGICALLYNEGATIVE FOR TRYPANOSOMA-CRUZI BUT AT A HIGH-RISK OF INFECTION

Authors
LEGUIZAMON MS RUSSOMANDO G DEARIAS AR SAMUDIO M CABRAL M GONZALEZCAPPA SM FRASCH ACC CAMPETELLA O
Citation
Ms. Leguizamon et al., USE OF TRANS-SIALIDASE INHIBITION ASSAY IN A POPULATION SEROLOGICALLYNEGATIVE FOR TRYPANOSOMA-CRUZI BUT AT A HIGH-RISK OF INFECTION, Clinical and diagnostic laboratory immunology, 5(2), 1998, pp. 254-255
Citations number
13
Categorie Soggetti
Immunology,"Infectious Diseases",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
5
Issue
2
Year of publication
1998
Pages
254 - 255
Database
ISI
SICI code
1071-412X(1998)5:2<254:UOTIAI>2.0.ZU;2-H
Abstract
trans-Sialidase inhibition assay (TIA) was employed in a population at high risk of Trypanosoma cruzi infection. From 20 serum samples that were negative by conventional serologic and parasitologic assays, 18 ( 90%) were reactive in TIA, providing further evidence of the higher se nsitivity of TIA and suggesting that the actual prevalence of T. cruzi infection might be underestimated.