EFFECT OF TREATMENT ON CYCLOSPORINE-INDUCED AND NIFEDIPINE-INDUCED GINGIVAL ENLARGEMENT - CLINICAL AND HISTOLOGIC RESULTS

The clinical and histologic responses to periodontal treatment of ging ival enlargements, induced when cyclosporine and nifedipine were admin istered singly or in combination, were evaluated. A significant correl ation was noted between plaque, gingivitis, and gingival overgrowth. S everity of enlargement appeared to be greater in patients on combined therapy All treatment approaches such as scaling roof planing gingivec tomy and periodontal flaps, and a combination of therapies, were effec tive in the management of gingival overgrowth up to 1 year after compl etion of treatment Adjunctive use of chlorhexidine was found to be ben eficial.