C. Tennstedt et al., ANGIOMYXOMA OF THE UMBILICAL-CORD IN ONE TWIN WITH CYSTIC DEGENERATION OF WHARTONS JELLY - A CASE-REPORT, Pathology research and practice, 194(1), 1998, pp. 55-58
We report the prenatal diagnosis of an angiomyxoma of the umbilical co
rd in a female fetus of a dizygotic twin pregnancy. The pregnant woman
was hospitalized at 18 weeks for exclusion of a suspected exomphalos.
Using high resolution ultrasound and color doppler, the umbilical tum
or (8x5x4 cm) was suspected to be an angiomyxoma without malformations
in the fetus. Neither chromosomal aberrations nor elevated alphafetop
rotein were found after amniocentesis. Serial examinations showed an i
ncrease in the size of the cystic mass without deterioration of the fe
tal condition. Macroscopical and microscopical examinations of the tum
or performed after delivery revealed an angiomyxoma with cystic degene
ration of Wharton's jelly. Tumors of the umbilical cord are rare anoma
lies and should be considered when using prenatal ultrasound for detec
tion of cystic lesions.