STUDY ON OXIDATION AND ELECTRON-TRANSFER IN PHOSPHORYLDIPEPTIDE METHYL-ESTER

Authors
CHU GS YAO SD CHEN JF ZHANG ZC ZHANG MW
Citation
Gs. Chu et al., STUDY ON OXIDATION AND ELECTRON-TRANSFER IN PHOSPHORYLDIPEPTIDE METHYL-ESTER, Gaodeng xuexiao huaxue xuebao, 19(2), 1998, pp. 305-308
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Gaodeng xuexiao huaxue xuebao → ACNP
ISSN journal
02510790
Volume
19
Issue
2
Year of publication
1998
Pages
305 - 308
Database
ISI
SICI code
0251-0790(1998)19:2<305:SOOAEI>2.0.ZU;2-8
Abstract
The Br-2(-.)-induced oxidation and electron transfer in N-(N-phosphory lmethionyl) tryptoyl methyl ester (NDM-TrpOMe) in aqueous solution wer e investigated using pulse radiolysis technique. The results indicated that the N-phosphoryl methioyl and tryptoyl group were oxidized by Br -2(-.) radicals simultaneously, and intramolecular electron transfer f rom tryptophan to the three-electron-bonded intermediate containing su lfur occured. Some kinetic parameters were determined and the reactive mechanism was deduced.