Giant pedunculated esophageal polyps are very rare, They may stay asym
ptomatic for a long time, and first come to the attention of the patie
nt and the clinician after regurgitation into the mouth. Regurgitation
, however, can be dangerous and has been known to lead to asphyxia and
death due to closure of the larynx by the polyp mass. For this reason
resection of the giant polyp is essential when it is discovered. We h
ave seen four cases of giant esophageal polyps (GEP) at our institutio
n. All four patients have undergone removal of the giant polyps. The h
istological diagnoses were fibrovascular polyp liposarcoma, hamartoma
and multiple lipomas. The mode of clinical presentation, radiological
appearances, variable histological diagnoses, and therapy options in t
hese four patients are presented along with a review of the literature
.