A case of chronic chemical meningitis occurring after a radical mastoi
dectomy is reported. Imaging and surgical findings were suggestive of
a dissemination of cholesteatoma debris within the subarachnoid spaces
. Chemical meningitis has been described in epidermoid and dermoid cys
t rupture. This report illustrates that clinicians should be aware of
this possible complication. Skull base imaging is mandatory before con
sidering the diagnosis of idiopathic meningitis, Only treatment of the
abnormal communication between cerebrospinal fluid and middle ear may
eradicate the origin of this rare meningitis.