NEUROCYTOMA RHABDOMYOMA (MYONEUROCYTOMA) OF THE CEREBELLUM/

Citation
L. Pal et al., NEUROCYTOMA RHABDOMYOMA (MYONEUROCYTOMA) OF THE CEREBELLUM/, Acta Neuropathologica, 95(3), 1998, pp. 318-323
Citations number
21
Categorie Soggetti
Neurosciences,"Clinical Neurology",Pathology
Journal title
ISSN journal
00016322
Volume
95
Issue
3
Year of publication
1998
Pages
318 - 323
Database
ISI
SICI code
0001-6322(1998)95:3<318:NR(OTC>2.0.ZU;2-G
Abstract
An unusual case of cerebellar neurocytoma with rhabdomyomatous differe ntiation in a 6-year-old boy is reported. Immunocytochemical and ultra structural features of the tumour were studied. Abortive synapse forma tion, the presence of clear vesicles and synaptophysin immunoreactivit y of the tumour cells indicated its intermediate neuronal differentiat ion, while the presence of myoblasts and myotubes and immunolabelling by desmin confirmed the rhabdomyomatous differentiation, In addition, the mesenchymal cells variably expressed neurofilament protein and gli al fibrillary acidic protein, suggesting inductive interaction between the neuroectodermal and ectomesenchymal elements and persistence of t he pleuripotential nature of the cells along the rhombic area of the b rain stem.