R. Zaldivar et al., LASER IN-SITU KERATOMILEUSIS FOR MYOPIA FROM -5.50 TO -11.50 DIOPTERSWITH ASTIGMATISM, Journal of refractive surgery, 14(1), 1998, pp. 19-25
PURPOSE: To determine the efficacy, predictability, safety, and short-
term stability of laser in situ keratomileusis (LASIK) in treating pat
ients with high myopia and astigmatism. METHODS: We retrospectively st
udied the results of our initial 119 eyes with myopia ranging from -5.
50 to -11.50 D and astigmatism less than 4.00 D that underwent LASIK w
ith the Nidek EC-5000 excimer laser. Follow-up was at 1 day, 1 month,
and 3 to 6 months; follow-up was 71% (84 eyes) at the 3 to 6 month vis
it (average 4.5 months). RESULTS: Of the 84 eyes with 3 to 6 months of
follow-up, mean baseline spherical equivalent refraction was -8.62 +/
- 1.27 D and mean cylinder was -1.84 +/- 1.02 D. Mean postoperative sp
herical equivalent refraction at the last examination was -0.61 +/- 0.
84 D and mean cylinder was -0.39 +/- 0.38 D, with 83% (70 eyes) achiev
ing a spherical equivalent refraction within +/-1.00 D of emmetropia,
and 56% (47 eyes) within +/-0.50 D. Mean regression of spherical equiv
alent from 1 day to 1 month was less than -0.50 D and refractions were
stable between 1 month and 3 to 6 months. An uncorrected visual acuit
y of 20/40 or better was noted in 84% (71 eyes) of these eyes on day 1
after surgery, in 75% (63 eyes) at 1 month, and in 77% (65 eyes) at 3
to 6 months. Twenty-two percent (18 eyes) of these eyes achieved 20/2
0 or better uncorrected visual acuity at 3 to 6 months; only 17% (14 e
yes) had 20/20 or better spectacle-corrected visual acuity before surg
ery. One patient lost two or more lines of spectacle-corrected visual
acuity at the last examination due to epidemic keratoconjunctivitis.