BACKGROUND: Laser in situ keratomileusis (LASIK) is an effective proce
dure to correct myopia. It may have complications related to the flap,
such as epithelial ingrowth and stromal melt. METHODS: We report on a
patient who developed extensive epithelial ingrowth and partial herat
olysis of the flap following LASIK, This complication was treated by l
ifting the flap and removing the epithelium from within the interface.
RESULTS: Progressive keratolysis (stromal melt) can result in irregul
ar astigmatism and loss of vision as well as photophobia and ciliary i
njection, The pathogenesis is not completely understood although the e
pithelial ingrowth in the interface is always present, and epithelial-
stromal interaction with production of proteases may be involved. CONC
LUSION: Epithelial ingrowth may develop in the lamellar interface afte
r LASIK and be associated with melting of the edge of the flap. This u
ndesirable complication can be successfully managed with early surgica
l removal of the epithelium and proper attachment of the flap.