Background: Climatotherapy at the Dead Sea is effective for patients w
ith psoriasis, atopic dermatitis, vitiligo, and other diseases. Althou
gh impressive improvement has been reported for patients with psoriasi
s, with a clearance rate of more than 80% after a 4-week stay, questio
ns regarding the safety of this treatment have arisen. Objective and M
ethods: We compare the mean UVB radiation intensities absorbed by psor
iatic patients undergoing a 4-week climatotherapy under supervision at
the DMZ Rehabilitation Clinic of Ein-Bokek (The Dead Sea, Israel), wi
th similar climatotherapy studies in Sweden and Switzerland, We also c
ompare the climatotherapy radiation dosages with the UVB intensities a
bsorbed by psoriatic patients in radiation cabins at seven university
clinics. Results: According to our individually computerized DMZ proto
col, a psoriasis patient with skin type IV is exposed during a 4-week
climatotherapy to a mean 3.11 J/cm(2) (148 MED) of UVB, similar to tha
t in Sweden and Switzerland. The range of the in-clinic annual phototh
erapy in the seven medical centers studied varied from 1.17 to 37.80 J
/cm(2) (56 to 1800 MED). Conclusion: When all relevant factors are tak
en into account, the mean UVB exposure dose at the Dead Sea is one of
the lowest reported for clearance of psoriatic plaques.