GENETIC SELECTION OF ALCOHOL PREFERENCE CAN BE COUNTERED BY CONDITIONING PROCESSES

Authors
GAUVIN DV VANECEK SA BAIRD TJ BRISCOE RJ VALLETT M HOLLOWAY FA
Citation
Dv. Gauvin et al., GENETIC SELECTION OF ALCOHOL PREFERENCE CAN BE COUNTERED BY CONDITIONING PROCESSES, Alcohol, 15(3), 1998, pp. 199-206
Citations number
37
Categorie Soggetti
Substance Abuse","Pharmacology & Pharmacy",Toxicology
Journal title
Alcohol → ACNP
ISSN journal
07418329
Volume
15
Issue
3
Year of publication
1998
Pages
199 - 206
Database
ISI
SICI code
0741-8329(1998)15:3<199:GSOAPC>2.0.ZU;2-4
Abstract
Twenty-four P rats and 24 NP rats were conditioned to consume 10% w/v alcohol in daily 0.5-h limited access periods using a modified version of Samson's sucrose fading procedure. Both P and NP rats demonstrated a strikingly similar day-to-day pattern of alcohol intakes. For the m ost parr, P rats drank more than NP rats, but by the middle of the fou rth month of drinking, P and NP rats were drinking equivalent amounts of alcohol. Both P and NP rats consumed alcohol in amounts similar to two outbred strains of rats (Wistar and Sprague-Dawley) previously con ditioned to drink alcohol in this laboratory. (C) 1998 Elsevier Scienc e Inc.