M. Hauser et al., RECURRENT PERICARDIALA EFFUSION DUE TO CH RONIC Q-FEVER INFECTION IN A 7 YEAR-OLD BOY, Monatsschrift fur Kinderheilkunde, 146(2), 1998, pp. 114-116
Q-fever is an infection caused by coxiella burnetti. Whilst the acute
form of the infection appears with uncharacteristic, influenca-like sy
mptoms,the chronic form shows symptoms of endocarditis mostly in patie
nts with congenital heart disease, valvular disorders, or during immun
osupression. Our patient, a 7 year old boy with congenital heart defec
t, developed a large pericardial effusion associated with high antibod
y levels as observed in chronic Q-fever. Discussion:This is reported t
o be extremely rare in childhood. The adequate antibiotic treatment in
paediatric patients seems to be the combination of erythromycin and r
ifampicin;the optimal duration of the antibiotic therapy remains undet
ermined, one year should be the minimum. The absence of phase I IgA an
d phase I IgG titers less than 400 seems to indicate definite cure.