PHYSIOPATHOLOGY OF THE RENIN-ANGIOTENSIN SYSTEM IN THE OVARY

The present review confirms the existence of the so-called ''ovarian-d erived prorenin-angiotensin cascade''. It also describes the physiopat hology of the system and, consequently, its role in the genesis of phe nomena concerning reproductive function such as ovulation, steroid syn thesis and folliculogenesis. Moreover, the ''ovarian-derived prorenin- angiotensin cascade'' appears to play an important role in the aetiopa thogenesis of diseases such as ovarian tumours, ovarian hyperstimulati on syndrome and ectopic pregnancy.