SALIVARY-GLAND SCINTIGRAPHY USING TECHNETIUM-99M-PERTECHNETATE AFTER AUTOTRANSPLANTATION OF THE SUBMANDIBULAR SALIVARY-GLAND IN THE CORRECTION OF DRY EYE
I. Lauer et al., SALIVARY-GLAND SCINTIGRAPHY USING TECHNETIUM-99M-PERTECHNETATE AFTER AUTOTRANSPLANTATION OF THE SUBMANDIBULAR SALIVARY-GLAND IN THE CORRECTION OF DRY EYE, European journal of nuclear medicine, 25(2), 1998, pp. 128-131
The aim of the study was to determine whether salivary gland scintigra
phy using technetium-99m pertechnetate is suitable for checking the vi
tality and function after autotransplantation of the submandibular sal
ivary gland in patients with dry eye syndrome. To this end, 56 scintig
raphic studies in 20 patients have so Ear been performed, In addition,
these scans were evaluated by a region of interest (ROI) technique in
order to examinee tracer uptake in the early and late stages after su
rgery. We have been able to prove that in this special respect, too, t
he salivary gland scintigraphy is suitable for assessing reliably the
vitality and function of the transplanted gland. The secretion into th
e eye and thus the patency of the efferent duct can also be displayed,
This proved to be particularly valuable in those cases in which at fi
rst no secretion could be seen in the clinical examination. In patient
s with uncertain excretory function, we were able to distinguish betwe
en non-vitality and lack of patency of the secretory duct. Using ROI e
valuation, no significant decrease in the salivary function has been d
etected in long-term follow-up, now extending to 1 year after surgery.