The Authors report on two patients, aged 21 and 24 months, affected by
chronic hyperinsulinemic hypoglicemia, who developped seizures at the
onset. Such patients seemed to us worth mentioning both for the pecul
iarity of the syndrome, which is rare in childhood, for the complex fu
nctional and instrumental diagnostic investigations to be performed in
order to attend a definite diagnosis, and for its therapeutic protoco
l still to be defined.