STRUCTURE AND DYNAMIC BEHAVIOR OF PROTEIN MOLECULES IN SOLUTION

The results of the investigation of structure and dynamic behavior of protein in solution by time-domain dielectric spectroscopy are present ed. The dipole correlation functions for myoglobin, lysozyme and RNase A solutions at different concentration, pH and temperature were obtai ned. The processes of the intramolecular interactions of myoglobin mol ecules, the pH-induced dimerization of lysozyme and thermal denaturati on of RNase A are discussed. (C) 1998 Published by Elsevier Science B. V. All rights reserved.