SOLUBLE CD23 AND IL-5 LEVELS IN THE SERUM AND CULTURE SUPERNATANTS OFPERIPHERAL-BLOOD MONONUCLEAR-CELLS IN A GIRL WITH CUTANEOUS PARAGONIMIASIS - CASE-REPORT

We examined the levels of soluble CD23 (sCD23) and IL-5 in the serum a nd culture supernatants of the peripheral blood mononuclear cells of a 9-year-old girl with cutaneous paragonimiasis without respiratory sym ptoms. Before treatment, levels of both sCD23 and IL-5 in her serum an d culture supernatants were elevated compared with those of controls. After successful treatment with praziquantel, sCD23 and IL-5 levels ra pidly reduced to normal levels. These results indicate that sCD23 and IL-5 are involved in the immune-mediated pathological responses seen i n paragonimiasis.