A FOURIER-TRANSFORM INFRARED SPECTROSCOPIC STUDY OF YEAST HEXOKINASE - CONFORMATIONAL-CHANGES UNDER INTERACTION WITH SUBSTRATES AND INHIBITORS

Authors
TRINQUIERDINET M BOISDON MT PERIE J WILLSON M
Citation
M. Trinquierdinet et al., A FOURIER-TRANSFORM INFRARED SPECTROSCOPIC STUDY OF YEAST HEXOKINASE - CONFORMATIONAL-CHANGES UNDER INTERACTION WITH SUBSTRATES AND INHIBITORS, SPECT ACT A, 54(2), 1998, pp. 367-373
Citations number
23
Categorie Soggetti
Spectroscopy
Journal title
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
ISSN journal
13861425 → ACNP
Volume
54
Issue
2
Year of publication
1998
Pages
367 - 373
Database
ISI
SICI code
1386-1425(1998)54:2<367:AFISSO>2.0.ZU;2-N
Abstract
The infrared (FTIR) spectroscopy study of several complexes of yeast h exokinase with substrates and inhibitors allows the determination of o pen and closed conformations of the protein. The analysis is based on a correlation between FTIR and X-ray data for one of the inhibitor-enz yme complexes of the study and from that reference, the features of th e amide I band hydration component. (C) 1998 Elsevier Science B.V.