GUIDELINES FOR THE INTERPRETATION OF ANALYTICAL TOXICOLOGY RESULTS AND UNIT OF MEASUREMENT CONVERSION FACTORS

Authors
Citation
Rj. Flanagan, GUIDELINES FOR THE INTERPRETATION OF ANALYTICAL TOXICOLOGY RESULTS AND UNIT OF MEASUREMENT CONVERSION FACTORS, Annals of clinical biochemistry, 35, 1998, pp. 261-267
Citations number
35
Categorie Soggetti
Biology,"Medical Laboratory Technology
ISSN journal
00045632
Volume
35
Year of publication
1998
Part
2
Pages
261 - 267
Database
ISI
SICI code
0004-5632(1998)35:<261:GFTIOA>2.0.ZU;2-4
Abstract
A data compilation has been published on the World Wide Web [http://ww w.leeds.ac.uk/acb/annals] which aims to assist in the interpretation o f analytical toxicology results in individual patients. 'Therapeutic' or 'normal' plasma/whole blood/urine concentrations, as well as the co ncentrations associated with serious toxicity (if known), for some 700 analytes of toxicological interest are given together with (when poss ible) relative atomic or formula masses, and mass/amount and amount/ma ss concentration conversion factors. This paper gives background and s upplementary information which should be borne in mind when providing interpretation or using the Web table. Supplementary tables listing (i ) common therapeutic drug monitoring assays and guidelines for interpr etation of results, (ii) emergency toxicology analyses which may influ ence active treatment, (iii) blood carboxyhaemoglobin saturation and c linical features of toxicity, (iv) information important when interpre ting the results of toxicology investigations, (v) factors which may a ffect interpretation of analytical toxicology results, and (vi) conver sion factors for volatile compounds are included.