G. Bonfiglio et al., ANTIBIOTIC-RESISTANCE IN PSEUDOMONAS-AERUGINOSA - AN ITALIAN SURVEY, Journal of antimicrobial chemotherapy, 41(2), 1998, pp. 307-310
In order to assess the current level of resistance to widely used anti
pseudomonal antibiotics in clinical isolates of Pseudomonas aeruginosa
, a national survey was undertaken. Fifteen hospitals throughout Italy
participated in the study. The University of Catania tested the antib
iotic susceptibility of 1005 consecutive clinically significant P. aer
uginosa collected from March to June 1995. Lack of susceptibility, acc
ording to NCCLS breakpoints, was at the I following rates: meropenem,
9.1%; imipenem, 19.3%; ceftazidime, 13.4%; carbenicillin, 27.3%; piper
acillin, 12%; ticarcillin/clavulanic acid, 22.8%; amikacin, 10.6%; and
ciprofloxacin, 31.9%. About half of the isolates (44.4%) were not sus
ceptible to at least one of the antibiotics tested.