Eb. Arushanyan et Mg. Vodolazhskaya, THE ROLE OF THE PINEAL-GLAND IN FORMATION OF TIME-CONDITIONED REACTIONS IN RATS, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 48(1), 1998, pp. 54-59
Pinealectomy impeded formation of time-conditioned reflex in the mode
of fixed intervals. This was accompanied by a shortening of reaction l
atency and runs as well as by an increase in the number of intertrial
responses. On the contrary, melatonin injection (0.1 mg/kg) facilitate
d conditioning by restricting the locomotion. It is suggested that pin
eal compounds have specific chronotropic properties.