FACILITATORY AND DEPRESSIVE EFFECTS OF IO NTOPHORETICALLY APPLIED ACETYLCHOLINE ON THE EARLY AND LATE COMPONENTS OF REACTIONS OF CAT MOTOR CORTEX NEURONS DURING PERFORMANCE OF CONDITIONED FOREPAW PLACING

Citation
Bv. Chernyshev et al., FACILITATORY AND DEPRESSIVE EFFECTS OF IO NTOPHORETICALLY APPLIED ACETYLCHOLINE ON THE EARLY AND LATE COMPONENTS OF REACTIONS OF CAT MOTOR CORTEX NEURONS DURING PERFORMANCE OF CONDITIONED FOREPAW PLACING, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 48(1), 1998, pp. 99-112
Citations number
27
Categorie Soggetti
Physiology,Neurosciences
ISSN journal
00444677
Volume
48
Issue
1
Year of publication
1998
Pages
99 - 112
Database
ISI
SICI code
0044-4677(1998)48:1<99:FADEOI>2.0.ZU;2-1
Abstract
The iontophoretic application of acetylcholine onto the motor cortex o f cats during the execution of conditioned placing reaction caused an increase in neuronal excitability and facilitation of ''extrinsic'' co nnections (manifested as an enhancement of primary responses to electr ical stimulation of the parietal cortex) and independent effect of sup presion, which could be seen only in the response components with long er latency, The functional significance of these oppositely directed e ffects of acetylcholine application is corroborated by statistically s ignificant changes in the motor response latency of the same direction s as the changes in neuronal responses. Such a correlation was observe d in a number of experiments.