Kl. Mcdowall et al., THE USE OF ABSOLUTE REFRACTORY PERIOD IN THE ESTIMATION OF EARLY POSTMORTEM INTERVAL, Forensic science international, 91(3), 1998, pp. 163-170
The estimation of the time since death (postmortem interval) is one of
the most difficult problems in forensic pathology. Most methods curre
ntly employed use temperature-based algorithms intended to model the c
ooling of the body after death and thus estimate the postmortem interv
al. These methods are subject to considerable inaccuracy but their rel
iability can be improved if a range of other observed criteria such as
lividity and rigor are also taken into consideration. The aim of the
present study was to investigate the feasibility of using the absolute
refractory period as an adjunct to the estimation of postmortem inter
val. The relationship between the 'postmortem interval' and the 'durat
ion of absolute refractory period' was investigated using the rat scia
tic nerve. A strong correlation between the duration of the absolute r
efractory period and the postmortem interval was observed. When both a
bsolute refractory period and temperature were used in conjunction, th
e strength of this correlation was increased. (C) 1998 Elsevier Scienc
e Ireland Ltd.