Rectal strictures are uncommon in young patients without a history of
malignancy, inflammatory bowel disease or previous surgery. Lymphogran
uloma venereum of the rectum has been described as a rare cause of rec
tal strictures in the western world, mainly in homosexual men and in b
lacks. It presents with nonspecific symptoms, rectal ulcer, proctitis,
anal fissures, abscesses and rectal strictures. Clinical and endoscop
ic findings as well as histology resemble Crohn's disease, which may b
e misdiagnosed. Serology is often positive for Chlamydia trachomatis b
ut negative serology is not uncommon. We present two young black women
who suffered from chronic diarrhoea, abdominal pain and weight loss.
There was no previous history and investigations showed in both cases
a long rectal stricture. Serology was positive in one patient. They we
re treated with erythromycin and azithromycin and they both underwent
an anterior resection of the rectum. Postoperative histology confirmed
the presence of lymphogranuloma venereum of the rectum. We conclude t
hat rectal lymphogranuloma venereum is a rare cause of rectal strictur
es but surgeons should be aware of its existence and include it in the
differential diagnosis of unexplained strictures in high-risk patient
s.