Several antiviral agents are available to treat viral illnesses in hea
lthy children. In some children, treatment with acyclovir is an altern
ative to vaccination for the treatment and prevention of chickenpox. A
cyclovir also can be useful in the treatment or prevention of herpes s
implex infections in neonates. Ribavirin, once recommended as routine
therapy for high-risk infants with respiratory syncytial virus disease
, is now reserved for use in selected children. Amantadine and rimanti
dine are effective against influenza type A and can be used to protect
children from influenza, as well as to lessen the duration and severi
ty of illness in those who are already ill.